Trusting God's sovereignty in all our circumstances

We often find it difficult to trust God in his sovereignty and providence particularly when things are hard or appear to us to make little sense. A couple of quotes from different sources to consider in such times.
 One from John Calvin highlighting the challenge we face: Many give mental assent to the truth of divine providence, but when confusion and difficulties come, few remain firmly persuaded of this truth.
Then this encouragement from Eugene Peterson: The only opportunity you will ever have to live by faith is in the circumstances you are provided this very day: this house you live in, this family you find yourself in, this job you have been given, the weather conditions that prevail at the ...moment.
Then supremely there is Jesus in Gethsemane, asking God the Father to take from him the cup of unimaginable suffering he was about to drink but ultimately trusting himself to the purpose and providence of God - nevertheless, not my will but yours be done. (Luke 22.42)
We can go to Jesus himself in such painful and perplexing circumstances when it is hard to trust  for    we do not have a high priest who is unable to sympathize with our weaknesses, but one who in every respect has been tempted as we are, yet without sin.  Let us then with confidence draw near to the throne of grace, that we may receive mercy and find grace to help in time of need.  (Hebrews 4.15-16)